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Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection

Leber A, Bassaganya-Riera J, Tubau-Juni N, Zoccoli-Rodriguez V, Viladomiu M, Abedi V, Lu P, Hontecillas R
PloS one 2016 Dec 9;11(12)
PMID: 27936058

Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa.

Verma M*, Erwin S*, Abedi V, Hontecillas R, Hoops S, Leber A, Bassaganya-Riera J, Ciupe SM. *Contributed equally to this work.
PloS one 2017 Jan 6;12(1)
PMID: 28060843

Novel Screening Tool for Stroke Using Artificial Neural Network

Abedi V, Goyal N, Tsivgoulis G, Hosseinichimeh N, Hontecillas R, Bassaganya-Riera J, Elijovich L, Metter JE, Alexandrov AW, Liebeskind DS, Alexandrov AV
Stroke 2017 Jun 1;48(6):1678-1681
PMID: 28438906

Modeling new immunoregulatory therapeutics as antimicrobial alternatives for treating Clostridium difficile infection

Leber A, Hontecillas R, Abedi V, Tubau-Juni N, Zoccoli-Rodriguez V, Stewart C, Bassaganya-Riera J
Artificial Intelligence in Medicine 2017 May 31;78:1-13
PMID: 28764868

Solving Immunology? Trends in Immunology

Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC.
Trends in Immunology 2017 Feb 1;38(2):116-127
PMID: 27986392

Modeling-Enabled Systems Nutritional Immunology.

Verma M., R. Hontecillas, V. Abedi, A. Leber, N.T. Juni, C. Philipson, A. Carbo, J. Bassaganya-Riera
Frontiers in Nutrition, section Nutritional Immunology 2016 Feb 16;3
PMID: 26909350

Modeling-Enabled Characterization of Novel NLRX1 Ligands.

Lu P, Hontecillas R, Abedi V, Kale S, Leber A, Heltzel C, Langowski M, Godfrey V, Philipson C, Tubau-Juni N, Carbo A, Girardin S, Uren A, Bassaganya-Riera J.
PLoS One 2015 Dec 29;10(12)
PMID: 26714018

Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection.

Philipson CW, Bassaganya-Riera J, Viladomiu M, Kronsteiner B, Abedi V, Hoops S, Michalak P, Kang L, Girardin SE, Hontecillas R.
PLoS One 2015 Sep 14;10(9)
PMID: 26367386

ENISI SDE: A New Web-Based Tool for Modeling Stochastic Processes.

Mei Y, Carbo A, Hoops S, Hontecillas R, Bassaganya-Riera J.
IEEE/ACM Trans Comput Biol Bioinform 2015 Mar 1;12(2):289-97
PMID: 26357217

Supervised learning methods in modeling of CD4+ T cell heterogeneity.

Lu P, Abedi V, Mei Y, Hontecillas R, Hoops S, Carbo A, Bassaganya-Riera J.
BioData Min 2015 Sep 4;8(27)
PMID: 26339293

Multiscale modeling of mucosal immune responses.

Mei Y, Abedi V, Carbo A, Zhang X, Lu P, Philipson C, Hontecillas R, Hoops S, Liles N, Bassaganya-Riera J.
BMC Bioinformatics 2015 Jan 1;16(Suppl 12)
PMID: 26329787

Sensitivity Analysis of an ENteric Immunity SImulator (ENISI)-Based Model of Immune Responses to Helicobacter pylori Infection.

Alam M, Deng X, Philipson C, Bassaganya-Riera J, Bisset K, Carbo A, Eubank S, Hontecillas R, Hoops S, Mei Y, Abedi V, Marathe M.
PLoS One 2015 Sep 1;10(9)
PMID: 26327290

Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection.

Leber A, Viladomiu M, Hontecillas R, Abedi V, Philipson C, Hoops S, Howard B, Bassaganya-Riera J.
PLoS One 2015 Jul 31;10(7)
PMID: 26230099

Computational modeling of heterogeneity and function of CD4+ T cells.

Carbo A, Hontecillas R, Andrew T, Eden K, Mei Y, Hoops S, Bassaganya-Riera J.
Front Cell Dev Biol 2014 Jul 29;2(31)
PMID: 25364738

Systems modeling of the role of interleukin-21 in the maintenance of effector CD4+ T cell responses during chronic Helicobacter pylori infection.

Carbo A, Olivares-Villagómez D, Hontecillas R, Bassaganya-Riera J, Chaturvedi R, Piazuelo MB, Delgado A, Washington MK, Wilson KT, Algood HM.
MBio 2014 Jul 22;5(4):e01243-14
PMID: 25053783

Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection.

Carbo A, Bassaganya-Riera J, Pedragosa M, Viladomiu M, Marathe M, Eubank S, Wendelsdorf K, Bisset K, Hoops S, Deng X, Alam M, Kronsteiner B, Mei Y, Hontecillas R.
PLoS One 2013 Sep 5;8(9)
PMID: 24039925

Systems modeling of molecular mechanisms controlling cytokine-driven CD4+ T cell differentiation and phenotype plasticity.

Carbo A, Hontecillas R, Kronsteiner B, Viladomiu M, Pedragosa M, Lu P, Philipson CW, Hoops S, Marathe M, Eubank S, Bisset K, Wendelsdorf K, Jarrah A, Mei Y, Bassaganya-Riera J.
PLoS Comput Biol 2013 Apr 1;9(4)
PMID: 23592971

Modeling the role of peroxisome proliferator-activated receptor y and microRNA-146 in mucosal immune responses to Clostridium difficile.

Viladomiu M, Hontecillas R, Pedragosa M, Carbo A, Hoops S, Michalak P, Michalak K, Guerrant RL, Roche JK, Warren CA, Bassaganya-Riera J.
PLoS One 2012 Jan 1;7(10)
PMID: 23071818

ENteric Immunity SImulator: a tool for in silico study of gastroenteric infections.

Wendelsdorf KV, Alam M, Bassaganya-Riera J, Bisset K, Eubank S, Hontecillas R, Hoops S, Marathe M.
IEEE Trans Nanobioscience 2012 Jan 1;11(3):273-88
PMID: 22987134

Computational modeling-based discovery of novel classes of anti-inflammatory drugs that target lanthionine synthetase C-like protein 2.

Lu P, Hontecillas R, Horne WT, Carbo A, Viladomiu M, Pedragosa M, Bevan DR, Lewis SN, Bassaganya-Riera J.
PLoS One Jan 1;7(42012)
PMID: 22509338

Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.

Lu P, Bevan DR, Lewis SN, Hontecillas R, Bassaganya-Riera J.
J Mol Model 2011 Jan 1;17(3):543-53
PMID: 20512604

Model of colonic inflammation: immune modulatory mechanisms in inflammatory bowel disease.

Wendelsdorf K, Bassaganya-Riera J, Hontecillas R, Eubank S.
J Theor Biol 2010 Jan 1;264(4):1225-39
PMID: 20362587

Virtual Screening as a Technique for PPAR Modulator Discovery.

Lewis SN, Bassaganya-Riera J, Bevan DR.
PPAR Res 2010 Jan 1
PMID: 19746174

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